Arise Study

PSP is a rare, progressive neurological disorder characterized by frequent falls, slurred speech, memory problems, and changes in personality. Because it is so uncommon, PSP is often misdiagnosed as Parkinson’s Disease. In fact, only approximately six per every 100,000 people worldwide are diagnosed with PSP.

Symptoms of PSP can be wide-ranging and may include the following:

  • Loss of balance (causing falls)
  • Stiffness
  • Problems moving one’s eyes up and down
  • Difficulty swallowing and speaking
  • Voice changes and the slowing of movements
  • Problems with memory
  • Changes in mood, behavior, and thinking

Researchers have found that, for patients with PSP, abnormal accumulations in the brain of a protein called tau are associated with the brain cells affected by the disease. A successful treatment for PSP has not yet been discovered, and more research is needed to further understand the relationship between PSP and the tau protein. That’s where the Arise Study comes in. The purpose of this research study is to test the efficacy and long-term safety and tolerability of an investigational study medication in patients with PSP.